DENTIN TUBULAR OCCLUSION

When the protective layer covering dentin near the base of the tooth becomes eroded or thinned, or if the gums recede, ultra-fine tubules that lead to the tooth nerve become exposed to outside stimuli, and short sharp pain can result. A range of studies, both in vitro and in situ, as observed by scanning electron microscope (SEM), show that SANGI's nano<mHAP> seals and forms a coating over exposed dentinal tubules,¹ and this has been substantiated by the significant relief of hypersensitivity reported by subjects in clinical trials.²

_{1. K.Ohta et al, Occlusion of Dentinal Tubules by Hydroxyapatite, J Dent Res 86:1759, New Orleans Abstracts, 2007

2. B.Amaechi et al, Clinical Efficacy in Relieving Dentinal Hypersensitivity of Nano-Hydroxyapatite-Containing Toothpaste, 2017 (publication pending)}